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Jmjd3 Plays Pivotal Roles in the Proper Development of Early-Born Retinal Lineages: Amacrine, Horizontal, and Retinal Ganglion Cells
PURPOSE: Trimethylation of histone H3 at lysine 27 (H3K27me3) is a critical mediator of transcriptional gene repression, and Jmjd3 and Utx are the demethylases specific to H3K27me3. Using an in vitro retinal explant culture system, we previously revealed the role of Jmjd3 in the development of rod b...
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| Published in: | Invest Ophthalmol Vis Sci |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
The Association for Research in Vision and Ophthalmology
2020
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7533738/ https://ncbi.nlm.nih.gov/pubmed/32986815 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.61.11.43 |
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