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Setd1a Plays Pivotal Roles for the Survival and Proliferation of Retinal Progenitors via Histone Modifications of Uhrf1

PURPOSE: The trimethylation of histone H3 at lysine 4 (H3K4me3) facilitates transcriptional gene activation, and Setd1a is the methyltransferase specific to H3K4. H3K4me3 has been reported to regulate rod photoreceptor differentiation; however, the roles H3K4me3 plays in retinal progenitor cell (RPC...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Deng, Xiaoyue, Iwagawa, Toshiro, Fukushima, Masaya, Suzuki, Yutaka, Watanabe, Sumiko
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8107498/
https://ncbi.nlm.nih.gov/pubmed/33938913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.62.6.1
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