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Methylation status of CpG sites in the NOTCH4 promoter region regulates NOTCH4 expression in patients with tetralogy of Fallot

Tetralogy of Fallot (TOF) is the most common form of cyanotic congenital heart disease (CHD). Although a lower methylation level of whole genome has been demonstrated in TOF patients, little is known regarding the DNA methylation changes in specific gene and its associations with TOF development. NO...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: Zhu, Yanjie, Ye, Ming, Xu, Hongfei, Gu, Ruoyi, Ma, Xiaojing, Chen, Mingwu, Li, Xiaodi, Sheng, Wei, Huang, Guoying
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7533461/
https://ncbi.nlm.nih.gov/pubmed/33000281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2020.11535
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