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DNA methylation status of NKX2-5, GATA4 and HAND1 in patients with tetralogy of fallot

BACKGROUND: NKX2-5, GATA4 and HAND1 are essential for heart development, however, little is known regarding their epigenetic regulation in the pathogenesis of tetralogy of fallot (TOF). METHODS: Methylation levels were measured in three regions of NKX2-5 (M1: -1596 bp ~ -1374 bp, M2: -159 bp ~ 217 b...

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Bibliografske podrobnosti
Main Authors: Sheng, Wei, Qian, Yanyan, Wang, Huijun, Ma, Xiaojing, Zhang, Ping, Diao, Lianwei, An, Quan, Chen, Long, Ma, Duan, Huang, Guoying
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3819647/
https://ncbi.nlm.nih.gov/pubmed/24182332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-6-46
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