SDF1/CXCR4 axis facilitates the angiogenesis via activating the PI3K/AKT pathway in degenerated discs

Symptomatic degenerative disc disease (DDD) is considered the leading cause of chronic lower back pain (LBP). As one of the main features of intervertebral disc degeneration (IDD), vascular ingrowth plays a crucial role in the progression of LBP. Stromal cell-derived factor 1 (SDF1) and its receptor...

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Detaylı Bibliyografya
Yayımlandı:Mol Med Rep
Asıl Yazarlar: Zhang, Hanxiang, Wang, Peng, Zhang, Xiang, Zhao, Wenrui, Ren, Honglei, Hu, Zhenming
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: D.A. Spandidos 2020
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7533460/
https://ncbi.nlm.nih.gov/pubmed/32901877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2020.11498
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