SDF1/CXCR4 axis facilitates the angiogenesis via activating the PI3K/AKT pathway in degenerated discs

Symptomatic degenerative disc disease (DDD) is considered the leading cause of chronic lower back pain (LBP). As one of the main features of intervertebral disc degeneration (IDD), vascular ingrowth plays a crucial role in the progression of LBP. Stromal cell-derived factor 1 (SDF1) and its receptor...

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Vydáno v:Mol Med Rep
Hlavní autoři: Zhang, Hanxiang, Wang, Peng, Zhang, Xiang, Zhao, Wenrui, Ren, Honglei, Hu, Zhenming
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2020
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Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7533460/
https://ncbi.nlm.nih.gov/pubmed/32901877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2020.11498
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