Differential effects of cisplatin on cybrid cells with varying mitochondrial DNA haplogroups

BACKGROUND: Drug therapy yields different results depending on its recipient population. Cisplatin, a commonly used chemotherapeutic agent, causes different levels of resistance and side effects for different patients, but the mechanism(s) are presently unknown. It has been assumed that this variati...

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Veröffentlicht in:PeerJ
Hauptverfasser: Abedi, Sina, Yung, Gregory, Atilano, Shari R., Thaker, Kunal, Chang, Steven, Chwa, Marilyn, Schneider, Kevin, Udar, Nitin, Bota, Daniela, Kenney, M. Cristina
Format: Artigo
Sprache:Inglês
Veröffentlicht: PeerJ Inc. 2020
Schlagworte:
Cell Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7533064/
https://ncbi.nlm.nih.gov/pubmed/33062421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.9908
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