Toll-like receptor 5 deficiency diminishes doxorubicin-induced acute cardiotoxicity in mice

Rationale: Clinical application of doxorubicin (DOX) is limited by its toxic cardiovascular side effects. Our previous study found that toll-like receptor (TLR) 5 deficiency attenuated cardiac fibrosis in mice. However, the role of TLR5 in DOX-induced cardiotoxicity remains unclear. Methods: To furt...

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Bibliografische gegevens
Gepubliceerd in:Theranostics
Hoofdauteurs: Ma, Zhen-Guo, Kong, Chun-Yan, Wu, Hai-Ming, Song, Peng, Zhang, Xin, Yuan, Yu-Pei, Deng, Wei, Tang, Qi-Zhu
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Ivyspring International Publisher 2020
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Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7532690/
https://ncbi.nlm.nih.gov/pubmed/33042267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.47516
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