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Toll-like receptor 5 deficiency diminishes doxorubicin-induced acute cardiotoxicity in mice
Rationale: Clinical application of doxorubicin (DOX) is limited by its toxic cardiovascular side effects. Our previous study found that toll-like receptor (TLR) 5 deficiency attenuated cardiac fibrosis in mice. However, the role of TLR5 in DOX-induced cardiotoxicity remains unclear. Methods: To furt...
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| Publicado no: | Theranostics |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Ivyspring International Publisher
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7532690/ https://ncbi.nlm.nih.gov/pubmed/33042267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.47516 |
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