An α(2)-adrenoceptor agonist: Dexmedetomidine induces protective cardiomyocyte hypertrophy through mitochondrial-AMPK pathway

Aims: Dexmedetomidine (Dex) as a highly selective α(2)-adrenoceptor agonist, was widely used anesthetic in perioperative settings, whether Dex induces cardiac hypertrophy during perioperative administration is unknown. Methods: The effects of Dex on cardiac hypertrophy were explored using the transv...

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Опубликовано в: :Int J Med Sci
Главные авторы: Weng, Xiaojian, Liu, Hua, Zhang, Xiaodan, Sun, Qianqian, Li, Cheng, Gu, Minglu, Xu, Yanyifang, Li, Shitong, Li, Weiwei, Du, Jianer
Формат: Artigo
Язык:Inglês
Опубликовано: Ivyspring International Publisher 2020
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Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7532472/
https://ncbi.nlm.nih.gov/pubmed/33029088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.47598
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