Evaluation of 3 molecular-based assays for microsatellite instability detection in formalin-fixed tissues of patients with endometrial and colorectal cancers

Microsatellite instability (MSI) status is routinely assessed in patients with colorectal and endometrial cancers as it contributes to Lynch syndrome initial screening, tumour prognosis and selecting patients for immunotherapy. Currently, standard reference methods recommended for MSI/dMMR (deficien...

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Vydáno v:Sci Rep
Hlavní autoři: Gilson, Pauline, Levy, Julien, Rouyer, Marie, Demange, Jessica, Husson, Marie, Bonnet, Céline, Salleron, Julia, Leroux, Agnès, Merlin, Jean-Louis, Harlé, Alexandre
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7532161/
https://ncbi.nlm.nih.gov/pubmed/33009475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-73421-5
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