Molecular alterations and targeted therapy in pancreatic ductal adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is a malignancy characterized by a poor prognosis and high mortality rate. Genetic mutations and altered molecular pathways serve as targets in precise therapy. Using next-generation sequencing (NGS), these aberrant alterations can be identified and used to de...

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Vydáno v:J Hematol Oncol
Hlavní autoři: Qian, Yunzhen, Gong, Yitao, Fan, Zhiyao, Luo, Guopei, Huang, Qiuyi, Deng, Shengming, Cheng, He, Jin, Kaizhou, Ni, Quanxing, Yu, Xianjun, Liu, Chen
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7532113/
https://ncbi.nlm.nih.gov/pubmed/33008426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-020-00958-3
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