High GFPT1 expression predicts unfavorable outcomes in patients with resectable pancreatic ductal adenocarcinoma

BACKGROUND: Glutamine-fructose-6-phosphate transaminase 1 (GFPT1) is the first rate-limiting enzyme of the hexosamine biosynthesis pathway (HBP), which plays a pivotal role in the progression of pancreatic ductal adenocarcinoma (PDAC). Therefore, we investigated the prognostic significance of GFPT1...

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Udgivet i:World J Surg Oncol
Main Authors: Gong, Yitao, Qian, Yunzhen, Luo, Guopei, Liu, Yu, Wang, Ruijie, Deng, Shengming, Cheng, He, Jin, Kaizhou, Ni, Quanxing, Yu, Xianjun, Wu, Weiding, Liu, Chen
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7849098/
https://ncbi.nlm.nih.gov/pubmed/33517899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12957-021-02147-z
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