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Sex differences in gene expression with galactosylceramide treatment in Cln3(Δex7/8) mice

BACKGROUND: CLN3 disease is caused by mutations in the CLN3 gene. The purpose of this study is to discern global expression patterns reflecting therapeutic targets in CLN3 disease. METHODS: Differential gene expression in vehicle-exposed mouse brain was determined after intraperitoneal vehicle/Galac...

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Veröffentlicht in:PLoS One
Hauptverfasser: Makoukji, Joelle, El-Sitt, Sally, Makhoul, Nadine J., Soueid, Jihane, Kadara, Humam, Boustany, Rose-Mary
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7531864/
https://ncbi.nlm.nih.gov/pubmed/33006978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0239537
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