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Global RNA editome landscape discovers reduced RNA editing in glioma: loss of editing of gamma-amino butyric acid receptor alpha subunit 3 (GABRA3) favors glioma migration and invasion

BACKGROUND: Gliomas are the most common and lethal type of intracranial tumors. With the current treatment regime, the median survival of patients with grade IV glioma (glioblastoma/GBM) remains at 14–16 months. RNA editing modifies the function and regulation of transcripts. The development of glia...

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Detalhes bibliográficos
Publicado no:PeerJ
Main Authors: Patil, Vikas, Pal, Jagriti, Mahalingam, Kulandaivelu, Somasundaram, Kumaravel
Formato: Artigo
Idioma:Inglês
Publicado em: PeerJ Inc. 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7531343/
https://ncbi.nlm.nih.gov/pubmed/33062411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.9755
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