The mRNA-edited form of GABRA3 suppresses GABRA3-mediated Akt activation and breast cancer metastasis

Metastasis is a critical event affecting breast cancer patient survival. To identify molecules contributing to the metastatic process, we analysed The Cancer Genome Atlas (TCGA) breast cancer data and identified 41 genes whose expression is inversely correlated with survival. Here we show that GABA(...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Nat Commun
Hlavní autoři: Gumireddy, Kiranmai, Li, Anping, Kossenkov, Andrew V., Sakurai, Masayuki, Yan, Jinchun, Li, Yan, Xu, Hua, Wang, Jian, Zhang, Paul J., Zhang, Lin, Showe, Louise C., Nishikura, Kazuko, Huang, Qihong
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4754346/
https://ncbi.nlm.nih.gov/pubmed/26869349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10715
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky