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Genetic Determinants of Reduced Arsenic Metabolism Efficiency in the 10q24.32 Region Are Associated With Reduced AS3MT Expression in Multiple Human Tissue Types

Approximately 140 million people worldwide are exposed to inorganic arsenic through contaminated drinking water. Chronic exposure increases risk for cancers as well as cardiovascular, respiratory, and neurologic diseases. Arsenic metabolism involves the AS3MT (arsenic methyltransferase) gene, and ar...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Toxicol Sci
Hauptverfasser: Chernoff, Meytal, Tong, Lin, Demanelis, Kathryn, Vander Griend, Donald, Ahsan, Habib, Pierce, Brandon L
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7531331/
https://ncbi.nlm.nih.gov/pubmed/32433756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfaa075
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