Rare, Protein-Altering Variants in AS3MT and Arsenic Metabolism Efficiency: A Multi-Population Association Study

BACKGROUND: Common genetic variation in the arsenic methyltransferase (AS3MT) gene region is known to be associated with arsenic metabolism efficiency (AME), measured as the percentage of dimethylarsinic acid (DMA%) in the urine. Rare, protein-altering variants in AS3MT could have even larger effect...

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Detalhes bibliográficos
Publicado no:Environ Health Perspect
Main Authors: Delgado, Dayana A., Chernoff, Meytal, Huang, Lei, Tong, Lin, Chen, Lin, Jasmine, Farzana, Shinkle, Justin, Cole, Shelley A., Haack, Karin, Kent, Jack, Umans, Jason, Best, Lyle G., Nelson, Heather, Griend, Donald Vander, Graziano, Joseph, Kibriya, Muhammad G., Navas-Acien, Ana, Karagas, Margaret R., Ahsan, Habibul, Pierce, Brandon L.
Formato: Artigo
Idioma:Inglês
Publicado em: Environmental Health Perspectives 2021
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Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8041273/
https://ncbi.nlm.nih.gov/pubmed/33826413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/EHP8152
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