Rare, Protein-Altering Variants in AS3MT and Arsenic Metabolism Efficiency: A Multi-Population Association Study

BACKGROUND: Common genetic variation in the arsenic methyltransferase (AS3MT) gene region is known to be associated with arsenic metabolism efficiency (AME), measured as the percentage of dimethylarsinic acid (DMA%) in the urine. Rare, protein-altering variants in AS3MT could have even larger effect...

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Publicat a:Environ Health Perspect
Autors principals: Delgado, Dayana A., Chernoff, Meytal, Huang, Lei, Tong, Lin, Chen, Lin, Jasmine, Farzana, Shinkle, Justin, Cole, Shelley A., Haack, Karin, Kent, Jack, Umans, Jason, Best, Lyle G., Nelson, Heather, Griend, Donald Vander, Graziano, Joseph, Kibriya, Muhammad G., Navas-Acien, Ana, Karagas, Margaret R., Ahsan, Habibul, Pierce, Brandon L.
Format: Artigo
Idioma:Inglês
Publicat: Environmental Health Perspectives 2021
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8041273/
https://ncbi.nlm.nih.gov/pubmed/33826413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/EHP8152
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