Metformin enhances protection in guinea pigs chronically infected with Mycobacterium tuberculosis

Tuberculosis (TB) is a chronic inflammatory disease that is often associated with alterations in systemic and cellular metabolism that resolves following successful antimicrobial drug treatment. We hypothesized that altered systemic glucose metabolism as a consequence of Mycobacterium tuberculosis (...

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Udgivet i:Sci Rep
Main Authors: Frenkel, Jessica D. Haugen, Ackart, David F., Todd, Alexandra K., DiLisio, James E., Hoffman, Siana, Tanner, Samantha, Kiran, Dilara, Murray, Megan, Chicco, Adam, Obregón-Henao, Andrés, Podell, Brendan K., Basaraba, Randall J.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7530990/
https://ncbi.nlm.nih.gov/pubmed/33004826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-73212-y
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