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Enantioselective synthesis of spiro[4H-pyran-3,3′-oxindole] derivatives catalyzed by cinchona alkaloid thioureas: Significant water effects on the enantioselectivity
An efficient stereoselective three-component reaction for the synthesis of functionalized spiro[4H-pyran-3,3′-oxindole] derivatives was realized through an organocatalyzed domino Knoevenagel/Michael/cyclization reaction using a cinchonidine-derived thiourea as the catalyst. Using water as the additi...
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| Publicado no: | Synth Commun |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7530948/ https://ncbi.nlm.nih.gov/pubmed/33012850 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/00397911.2019.1651866 |
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