Clarifying the Risk of Lung Disease in SZ Alpha-1 Antitrypsin Deficiency

Rationale: The ZZ genotype of alpha-1 antitrypsin deficiency (AATD) is associated with chronic obstructive pulmonary disease (COPD), even among never-smokers. The SZ genotype is also considered severe; yet, its effect on lung health remains unclear. Objectives: To determine the effect of SZ-AATD on...

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Detalhes bibliográficos
Publicado no:Am J Respir Crit Care Med
Main Authors: Franciosi, Alessandro N., Hobbs, Brian D., McElvaney, Oliver J., Molloy, Kevin, Hersh, Craig, Clarke, Louise, Gunaratnam, Cedric, Silverman, Edwin K., Carroll, Tomás P., McElvaney, Noel G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2020
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7530947/
https://ncbi.nlm.nih.gov/pubmed/32197047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.202002-0262OC
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