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Determination of secretory granule maturation times in pancreatic islet β-cells by serial block face scanning electron microscopy
It is shown how serial block-face electron microscopy (SBEM) of insulin-secreting β-cells in wild-type mouse pancreatic islets of Langerhans can be used to determine maturation times of secretory granules. Although SBEM captures the β-cell structure at a snapshot in time, the observed ultrastructure...
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| Publicat a: | J Struct Biol |
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| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7530942/ https://ncbi.nlm.nih.gov/pubmed/32736074 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2020.107584 |
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