BRAF status modulates Interelukin-8 expression through a CHOP-dependent mechanism in colorectal cancer

Inflammation might substantially contribute to the limited therapeutic success of current systemic therapies in colorectal cancer (CRC). Amongst cytokines involved in CRC biology, the proinflammatory chemokine IL-8 has recently emerged as a potential prognostic/predictive biomarker. Here, we show th...

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Bibliographic Details
Published in:Commun Biol
Main Authors: Conciatori, Fabiana, Bazzichetto, Chiara, Amoreo, Carla Azzurra, Sperduti, Isabella, Donzelli, Sara, Diodoro, Maria Grazia, Buglioni, Simonetta, Falcone, Italia, Shirasawa, Senji, Blandino, Giovanni, Ferretti, Gianluigi, Cognetti, Francesco, Milella, Michele, Ciuffreda, Ludovica
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7530707/
https://ncbi.nlm.nih.gov/pubmed/33004975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-01263-y
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