BRAF status modulates Interelukin-8 expression through a CHOP-dependent mechanism in colorectal cancer

Inflammation might substantially contribute to the limited therapeutic success of current systemic therapies in colorectal cancer (CRC). Amongst cytokines involved in CRC biology, the proinflammatory chemokine IL-8 has recently emerged as a potential prognostic/predictive biomarker. Here, we show th...

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Gepubliceerd in:Commun Biol
Hoofdauteurs: Conciatori, Fabiana, Bazzichetto, Chiara, Amoreo, Carla Azzurra, Sperduti, Isabella, Donzelli, Sara, Diodoro, Maria Grazia, Buglioni, Simonetta, Falcone, Italia, Shirasawa, Senji, Blandino, Giovanni, Ferretti, Gianluigi, Cognetti, Francesco, Milella, Michele, Ciuffreda, Ludovica
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7530707/
https://ncbi.nlm.nih.gov/pubmed/33004975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-01263-y
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