BRAF status modulates Interelukin-8 expression through a CHOP-dependent mechanism in colorectal cancer

Inflammation might substantially contribute to the limited therapeutic success of current systemic therapies in colorectal cancer (CRC). Amongst cytokines involved in CRC biology, the proinflammatory chemokine IL-8 has recently emerged as a potential prognostic/predictive biomarker. Here, we show th...

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Publicat a:Commun Biol
Autors principals: Conciatori, Fabiana, Bazzichetto, Chiara, Amoreo, Carla Azzurra, Sperduti, Isabella, Donzelli, Sara, Diodoro, Maria Grazia, Buglioni, Simonetta, Falcone, Italia, Shirasawa, Senji, Blandino, Giovanni, Ferretti, Gianluigi, Cognetti, Francesco, Milella, Michele, Ciuffreda, Ludovica
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7530707/
https://ncbi.nlm.nih.gov/pubmed/33004975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-01263-y
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