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Oxepinamide F biosynthesis involves enzymatic d-aminoacyl epimerization, 3H-oxepin formation, and hydroxylation induced double bond migration

Oxepinamides are derivatives of anthranilyl-containing tripeptides and share an oxepin ring and a fused pyrimidinone moiety. To the best of our knowledge, no studies have been reported on the elucidation of an oxepinamide biosynthetic pathway and conversion of a quinazolinone to a pyrimidinone-fused...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Zheng, Liujuan, Wang, Haowen, Fan, Aili, Li, Shu-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7530659/
https://ncbi.nlm.nih.gov/pubmed/33004788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18713-0
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