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Nanoparticle-based “Two-pronged” Approach to Regress Atherosclerosis by Simultaneous Modulation of Cholesterol Influx and Efflux
Reduction of lipoprotein uptake by macrophages and stimulation of cholesterol efflux are two essential steps required for atherosclerotic plaque regression. We used the optimized mannose-functionalized dendrimeric nanoparticle (mDNP)-based platform for macrophage-specific delivery of therapeutics to...
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| Publicado no: | Biomaterials |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7530139/ https://ncbi.nlm.nih.gov/pubmed/32853832 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2020.120333 |
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