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Importance of Evaluating Cell Cholesterol Influx With Efflux in Determining the Impact of Human Serum on Cholesterol Metabolism and Atherosclerosis

OBJECTIVE: Cholesterol efflux relates to cardiovascular disease but cannot predict cellular cholesterol mass changes. We asked whether influx and net flux assays provide additional insights. APPROACH AND RESULTS: Adapt a bidirectional flux assay to cells where efflux has clinical correlates and exam...

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Main Authors: Weibel, Ginny L., Drazul-Schrader, Denise, Shivers, Debra K., Wade, Alisha N., Rothblat, George H., Reilly, Muredach P., de la Llera-Moya, Margarita
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4005807/
https://ncbi.nlm.nih.gov/pubmed/24202308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.113.302437
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