BAF60a Deficiency in Vascular Smooth Muscle Cells Prevents Abdominal Aortic Aneurysm by Reducing Inflammation and Extracellular Matrix Degradation

OBJECTIVE: Currently, there are no approved drugs for abdominal aortic aneurysm (AAA) treatment, likely due to limited understanding of the primary molecular mechanisms underlying AAA development and progression. BAF60a, a unique subunit of the SWItch/Sucrose Non-Fermentable (SWI/SNF) chromatin remo...

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Vydáno v:Arterioscler Thromb Vasc Biol
Hlavní autoři: Chang, Ziyi, Zhao, Guizhen, Zhao, Yang, Lu, Haocheng, Xiong, Wenhao, Liang, Wenying, Sun, Jinjian, Wang, Huilun, Zhu, Tianqing, Rom, Oren, Guo, Yanhong, Fan, Yanbo, Chang, Lin, Yang, Bo, Garcia-Barrio, Minerva T., Lin, Jiandie D., Chen, Y. Eugene, Zhang, Jifeng
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7530061/
https://ncbi.nlm.nih.gov/pubmed/32787523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.120.314955
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