Cargando...
Mechanistic Insights into the Activation of Ester Prodrugs of 666-15
cAMP-response element binding protein (CREB) is an oncogenic transcription factor implicated in many different types of cancer. We previously reported the discovery of 666-15 as a potent inhibitor of CREB-mediated gene transcription. In an effort to improve the aqueous solubility of 666-15, amino es...
Gardado en:
| Publicado en: | Bioorg Med Chem Lett |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2020
|
| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7530057/ https://ncbi.nlm.nih.gov/pubmed/32730943 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2020.127455 |
| Tags: |
Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|