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Heat shock proteins accelerate the maturation of brain endothelial cell glucocorticoid receptor in focal human drug-resistant epilepsy
Pharmacoresistance in epilepsy is a major challenge to successful clinical therapy. Glucocorticoid receptor (GR) dysregulation can affect the underlying disease pathogenesis. We recently reported that local drug biotransformation at the blood-brain barrier is upregulated by GR, which controls drug-m...
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| Publicado en: | Mol Neurobiol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7530040/ https://ncbi.nlm.nih.gov/pubmed/32748370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-020-02043-9 |
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