Negative allosteric modulation of GluN1/GluN3 NMDA receptors

NMDA receptors are ligand-gated ion channels that mediate excitatory neurotransmission. Most native NMDA receptors are tetrameric assemblies of two glycine-binding GluN1 and two glutamate-binding GluN2 subunits. Co-assembly of the glycine-binding GluN1 with glycine-binding GluN3 subunits (GluN3A-B)...

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Publicado no:Neuropharmacology
Main Authors: Zhu, Zongjian, Yi, Feng, Epplin, Matthew P., Liu, Ding, Summer, Samantha L., Mizu, Ruth, Shaulsky, Gil, XiangWei, Wenshu, Tang, Weiting, Burger, Pieter B., Menaldino, David S., Myers, Scott J., Liotta, Dennis C., Hansen, Kasper B., Yuan, Hongjie, Traynelis, Stephen F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7530031/
https://ncbi.nlm.nih.gov/pubmed/32389749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2020.108117
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