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How Subgroup Analyses Can Miss the Trees for the Forest Plots: A Simulation Study

OBJECTIVE: Subgroup analyses of clinical trial data can be an important tool for understanding when treatment effects differ across populations. That said, even effect estimates from pre-specified subgroups in well-conducted trials may not apply to corresponding subgroups in the source population. W...

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Dades bibliogràfiques
Publicat a:J Clin Epidemiol
Autors principals: Webster-Clark, Michael, Baron, John A., Funk, Michele Jonsson, Westreich, Daniel
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7529905/
https://ncbi.nlm.nih.gov/pubmed/32565216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jclinepi.2020.06.020
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