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Progesterone increases blood glucose via hepatic progesterone receptor membrane component 1 under limited or impaired action of insulin

Hepatic gluconeogenesis is the main pathway for blood glucose maintenance activated during fasting. Retardation of insulin action, such as in diabetes mellitus, activates gluconeogenesis during the fed state. While the role of progesterone (P4) in diabetes is controversial, the P4 receptor, progeste...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Lee, Sang R., Choi, Woo-Young, Heo, Jun H., Huh, Jiyoung, Kim, Globinna, Lee, Kyu-Pil, Kwun, Hyo-Jung, Shin, Hyun-Jin, Baek, In-Jeoung, Hong, Eui-Ju
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7529793/
https://ncbi.nlm.nih.gov/pubmed/33005004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-73330-7
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