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Progesterone increases blood glucose via hepatic progesterone receptor membrane component 1 under limited or impaired action of insulin

Hepatic gluconeogenesis is the main pathway for blood glucose maintenance activated during fasting. Retardation of insulin action, such as in diabetes mellitus, activates gluconeogenesis during the fed state. While the role of progesterone (P4) in diabetes is controversial, the P4 receptor, progeste...

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Publicado en:Sci Rep
Main Authors: Lee, Sang R., Choi, Woo-Young, Heo, Jun H., Huh, Jiyoung, Kim, Globinna, Lee, Kyu-Pil, Kwun, Hyo-Jung, Shin, Hyun-Jin, Baek, In-Jeoung, Hong, Eui-Ju
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7529793/
https://ncbi.nlm.nih.gov/pubmed/33005004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-73330-7
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