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LptB-LptF coupling mediates closure of the substrate-binding cavity in the LptB(2)FGC transporter through a rigid-body mechanism to extract LPS
Lipopolysaccharides (LPS) are essential envelope components in many Gram-negative bacteria and provide intrinsic resistance to antibiotics. LPS molecules are synthesized in the inner membrane and then transported to the cell surface by the LPS transport (Lpt) machinery. In this system, the ATP-bindi...
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| Publié dans: | Mol Microbiol |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7529706/ https://ncbi.nlm.nih.gov/pubmed/32236984 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.14506 |
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