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Quantitative multiplex immunofluorescence analysis identifies infiltrating PD1(+)CD8(+) and CD8(+) T cells as predictive of response to neoadjuvant chemotherapy in breast cancer
BACKGROUND: This study aimed to explore the potentially predictive role and dynamic changes of immune checkpoints on T cell subsets in patients with breast cancer receiving neoadjuvant chemotherapies. METHODS: Fluorescent multiplex immunohistochemistry (mIHC) was used to stain CD4, CD8, PD1, TIM3, a...
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| Udgivet i: | Thorac Cancer |
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| Main Authors: | , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley & Sons Australia, Ltd
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7529566/ https://ncbi.nlm.nih.gov/pubmed/32894006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1759-7714.13639 |
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