A single-cell atlas of the mouse and human prostate reveals heterogeneity and conservation of epithelial progenitors

Understanding the cellular constituents of the prostate is essential for identifying the cell of origin for prostate adenocarcinoma. Here, we describe a comprehensive single-cell atlas of the adult mouse prostate epithelium, which displays extensive heterogeneity. We observe distal lobe-specific lum...

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Bibliographic Details
Published in:eLife
Main Authors: Crowley, Laura, Cambuli, Francesco, Aparicio, Luis, Shibata, Maho, Robinson, Brian D, Xuan, Shouhong, Li, Weiping, Hibshoosh, Hanina, Loda, Massimo, Rabadan, Raul, Shen, Michael M
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications, Ltd 2020
Subjects:
Cancer Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7529463/
https://ncbi.nlm.nih.gov/pubmed/32915138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.59465
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