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A single-cell atlas of the mouse and human prostate reveals heterogeneity and conservation of epithelial progenitors

Understanding the cellular constituents of the prostate is essential for identifying the cell of origin for prostate adenocarcinoma. Here, we describe a comprehensive single-cell atlas of the adult mouse prostate epithelium, which displays extensive heterogeneity. We observe distal lobe-specific lum...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Crowley, Laura, Cambuli, Francesco, Aparicio, Luis, Shibata, Maho, Robinson, Brian D, Xuan, Shouhong, Li, Weiping, Hibshoosh, Hanina, Loda, Massimo, Rabadan, Raul, Shen, Michael M
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7529463/
https://ncbi.nlm.nih.gov/pubmed/32915138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.59465
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