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Nonlinearities between inhibition and T-type calcium channel activity bidirectionally regulate thalamic oscillations
Absence seizures result from 3 to 5 Hz generalized thalamocortical oscillations that depend on highly regulated inhibitory neurotransmission in the thalamus. Efficient reuptake of the inhibitory neurotransmitter GABA is essential, and reuptake failure worsens human seizures. Here, we show that block...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7529462/ https://ncbi.nlm.nih.gov/pubmed/32902384 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.59548 |
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