Periodontal pathogens promote cancer aggressivity via TLR/MyD88 triggered activation of Integrin/FAK signaling that is therapeutically reversible by a probiotic bacteriocin

Epidemiological studies reveal significant associations between periodontitis and oral cancer. However, knowledge about the contribution of periodontal pathogens to oral cancer and potential regulatory mechanisms involved is limited. Previously, we showed that nisin, a bacteriocin and commonly used...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Kamarajan, Pachiyappan, Ateia, Islam, Shin, Jae M., Fenno, J. Christopher, Le, Charles, Zhan, Ling, Chang, Ana, Darveau, Richard, Kapila, Yvonne L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7529280/
https://ncbi.nlm.nih.gov/pubmed/33002094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008881
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