Periodontal pathogens promote cancer aggressivity via TLR/MyD88 triggered activation of Integrin/FAK signaling that is therapeutically reversible by a probiotic bacteriocin

Epidemiological studies reveal significant associations between periodontitis and oral cancer. However, knowledge about the contribution of periodontal pathogens to oral cancer and potential regulatory mechanisms involved is limited. Previously, we showed that nisin, a bacteriocin and commonly used...

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Udgivet i:PLoS Pathog
Main Authors: Kamarajan, Pachiyappan, Ateia, Islam, Shin, Jae M., Fenno, J. Christopher, Le, Charles, Zhan, Ling, Chang, Ana, Darveau, Richard, Kapila, Yvonne L.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7529280/
https://ncbi.nlm.nih.gov/pubmed/33002094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008881
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