Periodontal pathogens promote cancer aggressivity via TLR/MyD88 triggered activation of Integrin/FAK signaling that is therapeutically reversible by a probiotic bacteriocin

Epidemiological studies reveal significant associations between periodontitis and oral cancer. However, knowledge about the contribution of periodontal pathogens to oral cancer and potential regulatory mechanisms involved is limited. Previously, we showed that nisin, a bacteriocin and commonly used...

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發表在:PLoS Pathog
Main Authors: Kamarajan, Pachiyappan, Ateia, Islam, Shin, Jae M., Fenno, J. Christopher, Le, Charles, Zhan, Ling, Chang, Ana, Darveau, Richard, Kapila, Yvonne L.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2020
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7529280/
https://ncbi.nlm.nih.gov/pubmed/33002094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008881
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