Impact of Regulatory T Cells on Type 2 Alveolar Epithelial Cell Transcriptomes during Resolution of Acute Lung Injury and Contributions of IFN-γ

By enhancing tissue repair and modulating immune responses, Foxp3(+) regulatory T cells (Tregs) play essential roles in resolution from lung injury. The current study investigated the effects that Tregs exert directly or indirectly on the transcriptional profiles of type 2 alveolar epithelial (AT2)...

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Veröffentlicht in:Am J Respir Cell Mol Biol
Hauptverfasser: Mock, Jason R., Dial, Catherine F., Tune, Miriya K., Gilmore, Rodney C., O’Neal, Wanda K., Dang, Hong, Doerschuk, Claire M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Thoracic Society 2020
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7528916/
https://ncbi.nlm.nih.gov/pubmed/32543909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2019-0399OC
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