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Genetic and Pharmacological Inhibition of PAPP-A Protects Against Visceral Obesity in Mice

Pathogenicity of visceral adipose tissue (VAT) has been linked to the metabolic stress of enlarging mature adipocytes and a limited ability to recruit new adipocytes. One of the major distinguishing features of VAT preadipocytes is the high expression of the zinc metalloprotease, pregnancy-associate...

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Détails bibliographiques
Publié dans:Endocrinology
Auteurs principaux: Ramakrishna, Akhila, Bale, Laurie K, West, Sally A, Conover, Cheryl A
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7528556/
https://ncbi.nlm.nih.gov/pubmed/32888014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/endocr/bqaa160
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