Host genetics and tumor environment determine the functional impact of neutrophils in mouse tumor models

BACKGROUND: Neutrophils have been reported to have protumor, antitumor or neutral effects in cancer progression. The underlying causes for this functional variability are not clear. METHODS: We studied the role of neutrophils in six different mouse tumor models by intratumoral injection of antimicro...

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Veröffentlicht in:J Immunother Cancer
Hauptverfasser: van Elsas, Marit, Kleinovink, Jan Willem, Moerland, Matthijs, Feiss, Gary, Beyrend, Guillaume, Arens, Ramon, Mei, Hailiang, Nibbering, Peter H, Jirka, Silvana M, van Hall, Thorbald, van der Burg, Sjoerd H
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Publishing Group 2020
Schlagworte:
Basic Tumor Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7528431/
https://ncbi.nlm.nih.gov/pubmed/32998952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-000877
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