Nox4 regulates InsP(3) receptor‐dependent Ca(2+) release into mitochondria to promote cell survival

Cells subjected to environmental stresses undergo regulated cell death (RCD) when homeostatic programs fail to maintain viability. A major mechanism of RCD is the excessive calcium loading of mitochondria and consequent triggering of the mitochondrial permeability transition (mPT), which is especial...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Beretta, Matteo, Santos, Celio XC, Molenaar, Chris, Hafstad, Anne D, Miller, Chris CJ, Revazian, Aram, Betteridge, Kai, Schröder, Katrin, Streckfuß‐Bömeke, Katrin, Doroshow, James H, Fleck, Roland A, Su, Tsung‐Ping, Belousov, Vsevolod V, Parsons, Maddy, Shah, Ajay M
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7527947/
https://ncbi.nlm.nih.gov/pubmed/33001475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019103530
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