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Nox4 regulates InsP(3) receptor‐dependent Ca(2+) release into mitochondria to promote cell survival

Cells subjected to environmental stresses undergo regulated cell death (RCD) when homeostatic programs fail to maintain viability. A major mechanism of RCD is the excessive calcium loading of mitochondria and consequent triggering of the mitochondrial permeability transition (mPT), which is especial...

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Библиографические подробности
Опубликовано в: :EMBO J
Главные авторы: Beretta, Matteo, Santos, Celio XC, Molenaar, Chris, Hafstad, Anne D, Miller, Chris CJ, Revazian, Aram, Betteridge, Kai, Schröder, Katrin, Streckfuß‐Bömeke, Katrin, Doroshow, James H, Fleck, Roland A, Su, Tsung‐Ping, Belousov, Vsevolod V, Parsons, Maddy, Shah, Ajay M
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7527947/
https://ncbi.nlm.nih.gov/pubmed/33001475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019103530
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