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Leukemia-Associated Rho Guanine Nucleotide Exchange Factor and Ras Homolog Family Member C Play a Role in Glioblastoma Cell Invasion and Resistance

Glioblastoma (GBM) is the most common primary malignant brain cancer in adults. A hallmark of GBM is aggressive invasion of tumor cells into the surrounding normal brain. Both the current standard of care and targeted therapies have largely failed to specifically address this issue. Therefore, ident...

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Publicat a:Am J Pathol
Autors principals: Ding, Zonghui, Dong, Zhiwan, Yang, Yuping, Fortin Ensign, Shannon P., Sabit, Hemragul, Nakada, Mitsutoshi, Ruggieri, Rosamaria, Kloss, Jean M., Symons, Marc, Tran, Nhan L., Loftus, Joseph C.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7527857/
https://ncbi.nlm.nih.gov/pubmed/32693062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2020.07.005
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