Therapeutic Targeting of Myeloperoxidase Attenuates NASH in Mice

Myeloperoxidase (MPO) activity has been associated with the metabolic syndrome, cardiovascular and liver disease. Here, we evaluate the therapeutic potential of MPO inhibition on nonalcoholic steatohepatitis (NASH) and NASH‐induced fibrosis, the main determinant of outcomes. MPO plasma levels were e...

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Dettagli Bibliografici
Pubblicato in:Hepatol Commun
Autori principali: Koop, Anja Christina, Thiele, Nina Doreen, Steins, David, Michaëlsson, Erik, Wehmeyer, Malte, Scheja, Ludger, Steglich, Babett, Huber, Samuel, Schulze zur Wiesch, Julian, Lohse, Ansgar W., Heeren, Jörg, Kluwe, Johannes
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7527691/
https://ncbi.nlm.nih.gov/pubmed/33024915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1566
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