Synthesis and evaluation of N-isopropyl-p-[(11)C]methylamphetamine as a novel cerebral blood flow tracer for positron emission tomography

INTRODUCTION: Increases in fasting plasma glucose (PG) levels lead to a decrease in 2-deoxy-2-[(18)F]fluoro-d-glucose ([(18)F]FDG) uptake in the normal brain, especially in the precuneus, resulting in an Alzheimer’s disease (AD)-like uptake pattern. Therefore, patients with higher PG levels, such as...

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Detalhes bibliográficos
Publicado no:EJNMMI Res
Main Authors: Toyohara, Jun, Harada, Norihiro, Kakiuchi, Takeharu, Ohba, Hiroyuki, Kanazawa, Masakatsu, Tago, Tetsuro, Sakata, Muneyuki, Ishiwata, Kiichi
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2020
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7527401/
https://ncbi.nlm.nih.gov/pubmed/33000345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-020-00702-5
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