Ancestral function of Inhibitors-of-kappaB regulates Caenorhabditis elegans development

Mammalian IκB proteins (IκBs) exert their main function as negative regulators of NF-κB, a central signaling pathway controlling immunity and inflammation. An alternative chromatin role for IκBs has been shown to affect stemness and cell differentiation. However, the involvement of NF-κB in this fun...

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Publicado en:Sci Rep
Autores principales: Brena, David, Bertran, Joan, Porta-de-la-Riva, Montserrat, Guillén, Yolanda, Cornes, Eric, Kukhtar, Dmytro, Campos-Vicens, Lluís, Fernández, Lierni, Pecharroman, Irene, García-López, Albert, Islam, Abul B. M. M. K., Marruecos, Laura, Bigas, Anna, Cerón, Julián, Espinosa, Lluís
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7527347/
https://ncbi.nlm.nih.gov/pubmed/32999373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-73146-5
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