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CRISPR/Cas9-mediated correction of mutated copper transporter ATP7B
Wilson's disease (WD) is a monogenetic liver disease that is based on a mutation of the ATP7B gene and leads to a functional deterioration in copper (Cu) excretion in the liver. The excess Cu accumulates in various organs such as the liver and brain. WD patients show clinical heterogeneity, whi...
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| Gepubliceerd in: | PLoS One |
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| Hoofdauteurs: | , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Public Library of Science
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7526882/ https://ncbi.nlm.nih.gov/pubmed/32997714 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0239411 |
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